Broaden Your Chemistry Process Screening Horizons

Broaden Your Chemistry Process Screening Horizons ReactArray Microvate Rack Enables Investigation of a Wider Range of Solvents, Reagents and Catalysts. Improve Performance, Save Time and Costs. Optimization of chemical reactions can be complex, time consuming and expensive. Typically development reactions are run at a 10% dilution level in about 100 ml of solvent, consuming approximately 10g of starting material. Recently, the use of smaller reaction vessels combined with automated workstations has meant that more thorough process investigations can be carried out without increasing the demand for starting material. The ReactArray Workstation, from Anachem, is now recognised as the industry standard for process screening and optimization. The benefits of learning more about your chemistry faster has led to the demand for a reaction block that supports a larger number of small volume reactors. The ReactArray team in conjunction with the Pharmaceutical Industry has fulfilled this need by developing the Microvate Reaction Rack. This rack provides 48 reaction vessels with a volume capacity of 250µl to 2ml. These vessels are arranged in 12 independent temperature zones (-30 to 150 °C) with controlled temperature ramping, to increase the flexibility of the system. A reflux and inerting manifold is also available for broad chemistry scope. The racks are fully supported by ReactArray software. Large pharmaceutical companies are already benefiting from the power of the ReactArray Workstation fitted with a Microvate Rack. The more thorough investigations possible are uncovering less obvious reaction optima that would have otherwise been overlooked if more limited experiments had been employed. The Microvate provides the scope to investigate a wider range of solvents, reagents and catalysts so that better qualified reaction optima can be established. To find out how you can broaden your Chemistry Process Screening Horizons contact ReactArray, Anachem House, Charles Street, Luton, LU2 0EB, Telephone +44 (0) 1582 745065, Fax +44 (0) 1582 745104, Email ra-sales@reactarray.com, Web www.reactarray.com. ReactArray workstations have been developed through collaboration between Anachem and chemists within the pharmaceutical industry to provide a proven and robust concept that meets the demand for high throughput reaction screening and optimization. Today there are over 200 systems in use worldwide. Anachem is a leading supplier of laboratory equipment and services, established for over thirty five years with key expertise in liquid handling, chromatography, automation and process optimization solutions.

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