High Pressure Homogeniser Product Focus: Avestin EmulsiFlex C55

The difference in throughput between a benchtop and production scale high pressure homogneiser can be enormous, and so there is a need to bridge the gap between the two, via a system that offers all of the accessories and GMP-compliant modifications that a production-scale unit would offer, without the need to commit to an excessive throughput. The Avestin EmulsiFlex C55 does exactly that. This pilot scale unit is the smallest of the triplex pump systems available from Avestin, and is widely applied for applications including: Cell Disruption (Bacteria, Yeast, Algae, Insect and Mammalian cells) Liposomal Products Emulsions Particle Size Reduction Avestin EmulsiFlex C55 The three electrically-driven high pressure pumps operate intermittently, allowing for a flow rate of up to 55L/hr, and negligible pressure pulsation. By effectively nullifying this pressure pulsation, an even smoother homogenisation process is created, often reducing the required homogenisation pressure and number of passes to achieve the desired results. Despite having to account for a higher throughput, the head geometry within the homogenising valve (the point at which the sample is forced through a small orifice) maintains an exceptional degree of consistency with the benchtop units, optimising scalability. The unique Emulsiflex design ensures there are no “O”-rings or gaskets in the entire path of the product. This means less risk of contamination, easier cleaning and no leakage. The unique “dynamic” homogenizing valve design allows movement in accordance with sample viscosity; reducing the risk of blockage. The design aids to overcome many of the blockage issues associated with fixed valve design, allowing for smoother, efficient processing. With a minimum sample volume of only 100mL, the C55 is versatile in terms of suitable sample sizes, and the addition of an optional frequency inverter can allow for adjustable flow rates down to ~18L/hr, making smaller volumes easier to process, as well as reducing wear rates.[/vc_column_text][/vc_column][/vc_row] To read the full article please visit our website

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